Remote Infuse/Withdraw PHD ULTRA™ HPSI & PHD ULTRA™ XF Programmable Syringe Pumps

The PHD ULTRA™ is the solution for your most demanding fluidics applications. This pump represents the latest technology in syringe pumps and was developed utilizing the feedback of the world’s largest populations of syringe pump users.

Features:

• New patent pending drive mechanism for unmatched smooth flow, accuracy and precision
• High capacity – up to 800 ml with four 200 ml syringes
• Advanced programming for true multi methods without a PC
• Quick start methods
• Alpha/numeric keyboard without a PC
• Real and relative time clocks
• Icon operation
• New color LCD touch screen
• Up-front control knobs for ease of operation
• Vertical or horizontal orientation
• Adjustable linear force to 433 or 1000 lbs (depending upon model) across the entire flow range
• Daisy chain
• Remote configuration placement
• CE, ETL (UL, CSA), WEEE, EU RoHS, CB Scheme Approved
• 2-year warranty

Applications:

• Drug/Nutritional infusions
• Reaction chamber addition
• High pressure injection
• Highly corrosive fluids
• Remote pumping of hazardous material
• Continuous flow
• Flow programming
• Viscous solutions
• Large flow deliveries
• I/O interactive experiments

Remote Pump Model

The PHD ULTRA™ Remote Pumps consist of a control unit and syringe pumping mechanism all connected via a 30 foot RS-485 (IEEE-1394) cable. This makes the pump ideal for use in hazardous environments where the researcher is safer distanced from the material being pumped or for applications where you need to have the pumping mechanism inside a chamber. Every version of the PHD ULTRA™ is available in a remote model.

The PHD ULTRA™ will change the way you think about syringe pumps. There are three major areas which make the PHD ULTRA™ the new standard for syringe pumps:

1. Superior mechanical drive mechanism and syringe holding mechanics to achieve the highest performance of any syringe pump

2. EZ PRO Software and user interface allow easy programming of methods from simple to complex, all without the use of a PC (I/W and I/W Programmable models only)
– Preprogrammed methods for simple to complex operations that allow you to be up and running with the push of a button (I/W Programmable models only)
– LCD, high resolution color touch screen for powerful functionality, yet easy to use

3. Multiple levels of versatility
a. Configurations: push-pull, standard, remote, high pressure, multi racks
b. Connectivity: RS 232 and USB for PC; RS 485 for daisy chain

Harvard Apparatus introduces the next generation of syringe pumps, the PHD ULTRA™ for the most demanding applications.

Since 1901 Harvard Apparatus has been supporting bioresearch fluidics requirements with the culmination being the introduction of the first commercial syringe pump for bioresearch in 1956. Since 1956, over 70,000 satisfied syringe pump users around the world have made Harvard Apparatus syringe pumps the worlds #1 choice.

The PHD ULTRA™ Syringe Pump series is a family of high-accuracy, microliter- and milliliter-compatible pumps designed for versatile technical use including mass spectroscopy, calibration, drug and nutritional infusions, microdialysis, dispensing, chromatography and LC/HPLC.

Highest Accuracy and Precision
The PHD ULTRA™ syringe pump family has a fluidics drive mechanism which assures ease of use and high performance, for smoother, more accurate flow rates than any other syringe pump. Flow rates are accurate within 0.25% and reproducibility within 0.05%. A microprocessor-controlled, small step angle stepping motor drives a lead screw and pusher block. Advanced micro-stepping techniques are employed to further reduce the step angle to eliminate flow pulsation.

Advanced Programming Features:
• Flow Programming – Change the flow with time, volume or a triggered event as many times as you like
• Bolus – Inject a drug (or drugs) in a high quantity at once. The bolus injection can be made in time or volume.
• Concentration Delivery – Calibrate flow in concentration units of mg/kg easily so flow is calibrated to concentration of drug and animal weight.
• Gradients
• % ratio – up to three solvents
• I/O — dedicated and user defined I/O
• Pulsed Flow- so you can program the pulse easily

Widest Flow Rate Range
This pump is engineered to provide flow accuracy within 0.25% and reproducibility within 0.05%. Single or multi syringes from 0.5 µl to 140 ml pump at a range of 0.0001 µl/hr to 216 ml/min.

Maximum Experimental Versatility
The PHD ULTRA™ features true Multi-Pump Operation. The pump can be oriented vertically or horizontally for optimum experimental connectivity. This pump comes standard to hold 2 syringes, but can be purchase with 3 other syringe racks: 6 to 10 syringe rack, 4 x 140ml syringe rack and 4 x microliter syringe rack.

Easy-to-Use Interface
The PHD ULTRA™ color LCD touch screen graphic interface is divided into three basic areas: Operations Display, Message Area, and Navigation. This configuration allows you to easily move through all menu selections and data entry by gently touching the onscreen buttons with a finger or the tip of a soft, non-sharp object such as a pencil eraser.

The Methods Main or Quick Start screens are the primary home for the applications. From those screens you access all the commands needed to operate the PHD ULTRA™, as well as the main system settings.

The Message Area of the touch screen is used to display helpful instructions for the currently displayed screen. It is also used to display error or warning messages to indicate problem conditions in a Method or error conditions during pump operation.

The software is organized into three main Navigational branches, the quick start operations, preloaded/user-defined Methods, and systems settings. You can control operations directly with the touch screen or remotely from an independent computer or device via the external I/O interface.

Program Description
To operate the PHD ULTRA™, the user defines all the required parameters for infusing or withdrawing liquids through a Pump Control Method. The basic operation is a simple 4-step procedure:

1. Select a method
2. Enter operating parameters
3. Preview your method
4. Run your method

Applications
• Animal Infusions or Withdrawals – The PHD ULTRA™ will control the delivery of varying % of nutrients or drugs infused into animals, flush lines using catheters, needles, cannulae or microdialysis.
• Proportioning and Delivering of Mixtures – Mixing gradients or proportions with independent control of two liquids.
• Aerosol for Coating – The pump at high pressure can create an aerosol for the delivery of coating materials such as pharmaceutical tablets and aerosol studies.
• Delivery to Mass Spectroscopy – The delivery of fluids to the MS for calibration, matrix addition or ESI sample.
• Compensating Flows – The continuous infusion and simultaneous withdrawal of liquids for cell cultures or perfusion chambers.
• Dispensers/Injectors — Adhesives, Cell injection, MRI Dyes, Activators/Enzymes, Flow injection, Microreaction vessels, or Stereotaxic delivery.

Advanced GLP Documentation Features:
• Experiment parameter download information to PC
• Alpha/numeric capability

Accessories
A full range of accessories are compatible with the PHD ULTRA™ including syringe heaters, connectors, tubing, syringes and more.

Specifications